Mario G. Solari, MD

Assistant Professor of Plastic Surgery
Mario G. Solari, MD - headshot


Fax: 412-648-1987

Scaife Hall, Suite 6B

3550 Terrace Street

Pittsburgh, PA 15261, 


Dr. Mario G. Solari is an Assistant Professor in the Department of Plastic Surgery. He performs reconstructive surgery including head and neck, chest, abdominal wall, pelvic, and extremity reconstruction following trauma or cancer surgery. He specializes in microvascular reconstructive surgery.

Dr. Solari performed his undergraduate studies at The Johns Hopkins University in Baltimore and earned his medical degree from Tufts University in Boston. He completed his plastic surgery residency at the University of Pittsburgh. He took time away from clinical duty during residency to pursue a two-year extramural NIH fellowship (NRSA) studying the immunology of vascularized composite tissue allotransplantation (such as hand and facial tissue transplantation). After graduating from plastic surgery residency, he completed a reconstructive microsurgery fellowship at The University of Texas MD Anderson Cancer Center in Houston.

Dr. Solari is the Director of the Vascularized Composite Allotransplantation (VCA) Research Laboratory. His major research goals include elucidating the immunobiology of VCA and developing strategies that limit systemic immunosuppression, prevent acute and chronic rejection, promote allograft longevity, and maximize functional outcome. Dr. Solari is a member of the clinical reconstructive transplantation program. His laboratory is closely linked with the clinical program; the ultimate goal being the translation of new research findings into novel therapies that will improve the care and quality of life of our clinical hand and facial tissue allograft recipients.


Solari MG, Spangler E, Lee WP, Wollstein R. Fixation of comminuted distal radius fractures with a mixture of calcium phosphate and calcium sulfate cement. Hand Surg 2011. 16(2):223-8. | View Abstract »

Unadkat JV, Schneeberger S, Horibe EH, Goldbach C, Solari MG, Washington KM, Gorantla VS, Cooper GM, Thomson AW, Lee WP. Composite tissue vasculopathy and degeneration following multiple episodes of acute rejection in reconstructive transplantation. Am J Transplant 2010. 10(2): 251-261. | View Abstract »

Fischer J, Solari M, Shestak K. Enlarging breast mass in a patient with a history of polyurethane implants. Plast Reconstr Surg 2010. 125(2): 68e-70e. | View Abstract »

Unadkat JV, Schneeberger S, Goldbach C, Solari MG, Washington KM, Afrooz PN, Pulikkottil BJ, Zheng XX, Lee WP. Investigation of antibody-mediated rejection in composite tissue allotransplantation in a rat limb transplant model. Transplant Proc 2009. 41(2): 542-5. | View Abstract »

Solari MG, Washington KM, Sacks JM, Hautz T, Unadkat JV, Horibe EK, Venkataramanan R, Larregina AT, Thomson AW, Lee WPA. Daily topical tacrolimus therapy prevents skin rejection in a rodent hind limb allograft model. Plast Reconstr Surg 2009. 123(2 Suppl): 17-25. | View Abstract »

Washington KM,  Solari MG, Sacks JM, Horibe EK, Unadkat JV, Carvell GE, Simons DJ, Lee WPA. A model for functional recovery and cortical reintegration after hemifacial composite tissue allotransplantation. Plast Reconstr Surg 2009. 123(2 Suppl): 26-33. | View Abstract »

Solari MG, Srinivasan S, Boumaza I, Unadkat J, Harb G, Garcia-Ocana A, Feili-Hariri M. Marginal mass islet transplantation with autologous mesenchymal stem cells promotes long-term islet allograft survival and sustained normoglycemia. J Autoimmun 2009. 32(2): 116-24. | View Abstract »

Solari MG and Thomson AW. Human Dendritic Cells and Transplant Outcome. Transplantation 2008. 85(11):1513-1522. | View Abstract »

Ikeguchi R, Sacks JM, Unadkat JV, Solari M, Horibe EK, Thomson AW, Lee WP, Feili-Hariri M. Long-term survival of limb allografts induced by pharmacologically conditioned, donor alloantigen-pulsed dendritic cells without maintenance immunosuppression. Transplantation 2008. 85(2): 237-46. | View Abstract »

Mathes DW, Solari MG, Randolph MA, Gazelle GS, Yamada K, Huang, CA, Sachs DH, Lee WP. Transplantation tolerance following prenatal inoculation with adult bone marrow. Transplantation 2005. 80(9):1300-8. | View Abstract »

Mathes DW, Randolph MA, Solari MG, Nazzal JA, Nielsen GP, Arn JS, Sachs DH, Lee WPA. Split tolerance to a composite tissue allograft in a swine model. Transplantation 2003. 75(1): 25-31. | View Abstract »

Mathes DW, Bourget JL, Randolph MA, Solari MG, Wu A, Sachs DH, Lee WP. Tolerance to vascularized musculoskeletal allografts. Transplant Proc 2001. 33(1-2): 616-7. | View Abstract »

Orgill DP, Solari MG, Barlow MS, O'Connor NE. A finite-element model predicts thermal damage in cutaneous contact burns. J Burn Care Rehabil 1998. 19(3): 203-9. | View Abstract »

Research Lab Affiliation

Lab Role