Gregory M. Cooper, PhD

Assistant Professor of Plastic Surgery
Gregory M. Cooper, PhD - headshot



3510 Rangos Research Center

4401 Penn Avenue

Pittsburgh, PA 15224, 


Gregory M. Cooper, Ph.D. is faculty of the Departments of Plastic Surgery, Oral Biology, and Bioengineering. After growing up in central Pennsylvania, he received his bachelor’s degrees from the University of Pittsburgh in Anthropology and Biology and his doctorate degree from the Department of Bioengineering at the University of Pittsburgh.

Dr. Cooper is interested in bone biology, bone tissue engineering, and craniosynostosis. He functions as the Director of the Pediatric Craniofacial Biology Laboratory at Children’s Hospital of Pittsburgh and hopes to improve the treatment of children with bone-related problems through collaborative translational research.


Cooper GM, Mooney MP, Gosain AK, Campbell PG, Losee JE, Huard J. Testing the critical-size in calvarial bone defects: revisiting the concept of a critical-sized defect. Plast Reconstr Surg. 2010; 125(6): 1685-1692. | View Abstract »

Cooper GM, Miller ED, DeCesare GE, Usas A, Lensie EL, Bykowski MR, Huard J, Weiss LE, Losee JE, Campbell PG. Inkjet-Based Biopatterning of BMP-2 to Spatially Control Calvarial Bone Formation. Tissue Eng Part A. 2010; 16(5):1749-59. | View Abstract »

Cray JJ Jr., Burrows AM, Vecchione L, Lensie EL, DeCesare GE, Campbell A, Finegold DN, Losee JE, Siegel MI, Cooper GM, Mooney MP. Effects of Flutamide Therapy on Craniofacial Growth and Development in a Model of Craniosynostosis. J Craniofac Surg. 2010; 21(3):711-718. | View Abstract »

Cooper GM, Lensie EL, Cray JJ, DeCesare GE, Smalley MA, Losee JE, Mooney MP. BMP4 response in wild-type and craniosynostotic rabbit bone cells. Plast Reconstr Surg. 2010; 125(5):1403-1411. | View Abstract »

Cooper GM, Lensie EL, Cray JJ, Bykowski MR, DeCesare GE, Smalley MA, Mooney MP, Campbell PG, Losee JE. Direct comparison of progenitor cells derived from adipose, muscle, and bone marrow from wild-type or craniosynostotic rabbits. Plast Reconstr Surg. 2011; 127(1):88-97. | View Abstract »

Kinsella CR Jr., Cray JJ Jr., Cooper GM, Pollack IF, Losee JE. Parasagittal suture after strip craniectomy. J Craniofac Surg. 2011; 22(1):66-67. | View Abstract »

Cray JJ Jr., Burrows AM, Vecchione L, Caccamese JF, Losee JE, Moursi AM, Siegel MI, Cooper GM, Mooney MP. Blocking BMP function using in vivo noggin therapy does not rescue premature suture fusion in rabbits with delayed onset craniosynostosis. Plast Reconstr Surg. 2011; 127(3):1163-1172. | View Abstract »

Kinsella CR Jr., Cray JJ, Lensie EL, Burrows AM, Vecchione L, Smith DM, Mooney MP, Cooper GM, Losee JE. Recombinant human bone morphogenetic protein-2-induced craniosynostosis and growth restriction in the immature skeleton. Plast Reconstr Surg. 2011; 127(3):1173-81. | View Abstract »

DeCesare GE, Cooper GM, Smith DM, Cray JJ Jr., Lensie EL, Kinsella CR Jr., Mooney MP, Losee JE. Novel Animal Model of Calvarial Defect in an Infected Unfavorable Wound: Reconstruction with rhBMP-2. Plast Reconstr Surg. 2011; 127(2):588-594. | View Abstract »

Cray JJ Jr., Gallo PH, Durham EL, Losee JE, Mooney MP, Kathju S, Cooper GM. Molecular analysis of coronal perisutural tissues in a craniosynostotic rabbit model using polymerase chain reaction-suppression subtractive hybridization (PCR SSH). Plast Reconstr Surg. 2011; 128(1): 95-103. | View Abstract »

Cray J Jr, Durham E, Smalley M, Finegold D, Siegel M, Losee J, Mooney M, Cooper GM. The effects of testosterone on craniosynostotic calvarial cells: a test of the gene/environmental model of craniofacial anomalies. Orthod Craniofac Res. 2011 Aug; 14(3):149-155. | View Abstract »

Kinsella CR Jr, Bykowski MR, Lin AY, Cray JJ, Smith DM, Lensie EL, DeCesare GE, Mooney MP, Cooper GM, Losee JE. BMP-2-Mediated Regeneration of Large Scale Cranial Defects in the Canine: An Examination of Different Carriers. Plast Reconstr Surg. 2011; 127(5):1865-1873. | View Abstract »

Kinsella CR, Jr., Cray JJ, Smith DM, Rottgers SA, Mooney MP, Cooper GM, Losee JE. Novel Model of Calvarial Defect in an Infected Unfavorable Wound: Reconstruction With rhBMP-2. Part II. J Craniofac Surg. 2012; 23(2):410-4. | View Abstract »

Cooper GM, Durham EL, Cray JJ, Jr., Siegel MI, Losee JE, Mooney MP.  Tissue interactions between craniosynostotic dura mater and bone. J Craniofac Surg. 2012; 23(3):919-924. | View Abstract »

Smith DM, Cray JJ Jr., Weiss LE, Dei Fei EK, Shakir S, Rottgers SA, Losee JE, Campbell PG, Cooper GM. Precise Control of Osteogenesis for Craniofacial Defect Repair: The Role of Direct Osteoprogenitor Contact in BMP-2-Based Bioprinting. Ann Plast Surg. 2012; 69(4):485-488. | View Abstract »

Research Lab Affiliation

Lab Role